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Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development

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Springer , Heidelberg, New York
SeriesEpigenetics and human health
The Physical Object
FormatE-book
Pagination1 online resource (xiii, 416 pages)
ID Numbers
Open LibraryOL26419931M
ISBN 103642451985
ISBN 139783642451980

This book describes the intricate processes involved in the development of blood cells across a range of organisms from drosophila and fish at one end, and mammals at the other end. It contains individual chapters devoted to describing the epigenetic and transcriptional mechanisms regulating hematopoiesis in the different organisms and.

Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development (Epigenetics and Human Health): Medicine & Health Science Books @ hor: Constanze Bonifer. £ Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development (Epigenetics and Human Health) Hardcover – 26 Mar.

by Constanze Bonifer (Editor), Peter N. Cockerill (Editor)Format: Hardcover. Lee "Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development" por disponible en Rakuten Kobo.

During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, Brand: Springer Berlin Heidelberg. Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development.

Editors: Bonifer, Constanze, Cockerill, Peter (Eds.) Free Preview. Save on Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development by Constanze Bonifer.

Shop your textbooks from ZookalAU today. During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and. Bai X. () Epigenetic and Transcriptional Mechanisms Regulating Blood Cell Development in Zebrafish.

In: Bonifer C., Cockerill P. (eds) Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Epigenetics and Human Health. Springer, Berlin, Heidelberg.

First Online 05 February Laslo P., Stopka T. () Transcriptional and Epigenetic Regulation in the Development of Myeloid Cells: Normal and Diseased Myelopoiesis.

In: Bonifer C., Cockerill P. (eds) Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Epigenetics and Human Health. Springer, Berlin, Heidelberg. Badenhorst P. () What Can We Learn from Flies: Epigenetic Mechanisms Regulating Blood Cell Development in Drosophila.

In: Bonifer C., Cockerill P.

Description Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development FB2

(eds) Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Epigenetics and Human Health. Springer, Berlin, Heidelberg. First Online 05 February In: Bonifer C., Cockerill P. (eds) Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development.

Epigenetics and Human Health. Springer, Berlin, Heidelberg. from book Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development (pp) Transcriptional and Epigenetic Regulation in the Development of Myeloid Cells.

Get this from a library. Transcriptional and epigenetic mechanisms regulating normal and aberrant blood cell development. [Constanze Bonifer; Peter N Cockerill;] -- In recent years, great progress has been made in the identification of the molecular players involved in the epigenetic control of gene expression during development.

The work of many laboratories. Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Constanze Bonifer & Peter N. Cockerill, Editors Chapter The Molecular Basis of Normal Erythroid/Megakaryocyte development and Mechanisms of Epigenetic/Transcriptional Deregulation Leading to Erythroleukemia and Thalassemia.

The above transcriptional program of OL differentiation and myelination is highly influenced and reliant on a parallel process of epigenetic regulation. Epigenetic regulation, which by definition is mediated through mechanisms other than changes in the targeted DNA sequence, is crucial for cell growth, differentiation, and organogenesis.

Autore: Bonifer - Cockerill, Categoria: Libri, Prezzo: € ,11, Lunghezza: pagine, Editore: Springer Verlag, Titolo: Transcriptional and Epigenetic Mechanisms. Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development.

Constanze Bonifer. $ Epigenetic Regulation of Lymphocyte Development. por. Current Topics in Microbiology and Immunology (Book ) Comparte tus pensamientos Completa tu reseña.

In addition to transcriptional mechanisms, levels of EBF1 in B cells are also controlled by posttranslational mechanisms.

The carboxy-terminal domain of zinc finger protein (Evi3/Zfp/ZNF) interacts with EBF1 and inhibits its DNA binding in vitro and in transfected cells [], [].

Request PDF | Epigenetic Control of Immune T Cell Memory | The main role of the immune system is to protect against infections caused by invading. Transcriptional regulation of immune cell differentiation and development; Epigenetic Mechanisms Regulating Blood Cell Development in Drosophila.

In: Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Bonifer, C. & Cockerill, P. (eds.). Springer Verlag, p.

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Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development During vertebrate hematopoiesis many special-ized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes.

To tightly control the enormous proliferative. In addition to transcription factor binding to promoters, regulation of transcription early in development is achieved via epigenetic mechanisms.

The term epigenetics, as used and accepted today, is defined as “heritable changes in gene function that cannot be explained by changes in DNA sequence” (Russo et al.

The Role of Epigenetic Mechanisms in Autoimmunity. The role of this article has up until now been to introduce basic concepts of chromatin structure and the epigenetic mechanisms that control the function of the genome in normal cells and in disease.

Author(s): Bonifer,Constanze; Cockerill,Peter N Title(s): Transcriptional and epigenetic mechanisms regulating normal and aberrant blood cell development/ Constanze Bonifer, Peter N.

Details Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development EPUB

Cockerill, editors. Epigenetic and transcriptional mechanisms regulating the development of the hematopoietic system in mammals by Maud Fleury, Flor M. Perez-Campo, Guilherme Costa, Georges Lacaud and Valerie Kouskoff Epigenetics and Human Reproduction by Sophie Rousseaux,available at Book Depository with free delivery worldwide.

Transcriptional and Epigenetic Regulation of Microglia in Health and Disease Hana Yeh1,2, *and Tsuneya Ikezu 2,3, stem cells found in peripheral blood and bone marrows that can develop into all types of blood cells.

and activates gene expression during immune cell development [24,25]. Microglia. Differentiation of hematopoietic stem cells into antibody-producing B cells requires a complex epigenetic regulatory mechanism that produces changes in chromatin structure throughout B cell development.

Altered DNA demethylation patterns within gene bodies outside of CpG islands are essential for the correct differentiation and function.

Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development in the development of blood cells across a range of organisms from drosophila and fish at one.

Krüppel-like factor 1 (KLF1) or erythroid Krüppel-like factor is an essential transcription factor for erythroid development and was found to be key in the regulation of many facets of blood development.

KLF1 is expressed in the developing blood as well as being weakly expressed in mast cells. We have identified a simple epigenetic mechanism underlying the establishment and maintenance of immunological memory in T cells. By studying the transcriptional regulation of inducible genes we.

Epigenetic Regulation and Epigenomics. Robert A. Meyers. $ Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Constanze Bonifer. $ Genomic Elements in Health, Disease and Evolution. Kyriacos Felekkis. $Maud Fleury, Flor M. Perez-Campo, Guilherme Costa, Georges Lacaud, Valerie Kouskoff, Epigenetic and Transcriptional Mechanisms Regulating the Development of the Haematopoietic System in Mammals, Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development, /_4, ().

Bonifer C, Cockerill PN (eds) Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development. Epigenetics and Human Health, Springer, Heidelberg, ISBN View all publications in research portal.